Memorial Bone & Joint Research Foundation
Memorial Bone & Joint Research Foundation

Current Projects

  • Clinical Joint Registry
    The joint registry is a collection of data on individuals who have had joint disease including follow up and evaluation of response to therapy. The purpose of the joint registry is to establish a comprehensive patient database to collect and store clinical data associated with use of implantable joint devices to permit quantitative evaluation and qualitative assessment of factors impacting health outcome.

  • Uniglide Mobile Bearing Knee Replacement
    Dr. Stefan Kreuzer is one of co-lead investigators participating in the Uniglide Mobile Bearing Partial Knee Replacement study, and implanted his first study patient on December 1, 2008. This study compares FDA approved partial knee implants with an advanced new type of implant. Actively enrolling in this study.

  • Cormet Post Approval Surveillance Study
    Dr. Kreuzer is one of the lead investigators for the Cormet Post Approval Study, implanted the first hip replacement study patient on April 21, 2008. Subjects received hip replacement with the minimally invasive anterior approach, allowing fast recuperation time for undergoing an advanced hip replacement procedure with the FDA approved implant from Corin USA. Enrollment for this study is now complete, and patients are being followed up.

  • Anterior Hip Resurfacing
    The direct anterior approach to Hip Resurfacing is one of the minimally invasive techniques used in hip resurfacing surgery. Continuing orthopedic experience suggests that this procedure may offer several advantages

  • Makoplasty
    The MAKOplasty Unicodylar Knee Resurfacing procedure is a FDA approved treatment option for patients who suffer from osteoarthritis damage in the medial (inner) portion of the knee.

  • Post THA Muscle Enhancing Drug Study
    This studies the effect of a new drug sponsored by a leading pharmaceutical company on the drug’s muscle strengthening capability in older adults with weak muscles. After Total Hip Arthroplasty (THA) these adults may not regain good activity due to weakness of muscles, which this study drug seeks to alleviate. The patients are followed up to assess improvement in muscle mass and their activities to see the beneficial effects if any.Actively enrolling in this study.

  • Hip Fracture Related Bone Strengthening Drug Study
    Some fractures of the hip (neck of the femur) are hard to heal and break again even after being repaired.  This group of elderly and frail individuals may benefit from a bone strengthening medication approved by the FDA for some other uses (e.g. bone weakening after menopause).  This study seeks to find out if the drug will be advantageous to these patients. Actively enrolling in this study.

  • Prosthetic Infection Diagnosis Technique Study
    Artificial joints (Prostheses) are sometimes infected beyond cure and must be then taken out with another surgery followed by yet another new prosthesis implanted (Revision surgery).  Since the signs and symptoms to establish the infection of these prostheses are still not a 100% sure this study seeks to establish the utility of a new form of diagnostic mechanism.  With the use of a new compound coupled with radiological imaging techniques a better way of diagnosing these troubling infections may be discovered. Pending the beginning of enrollment in this study.

  • Comparison of Anterior Approach Hip Replacement with Traditional THA
    The direct anterior approach to Hip Replacement is one of the most advanced and difficult minimally invasive techniquesfor Total Hip Arthroplasty (THA). Since Dr. Kreuzer is performing these in patients who have had the other hip replaced in the past with the traditional approach, it provides us a unique opportunity to compare the outcomes of the two kinds of surgeries in the same patient. This study is still in its design phase and we are eagerly awaiting funds to start.

  • Retrospective Analysis of Bilateral Hip Replacement Whereby One Side Received the Direct Anterior Approach (MRI Study):
    The Primary objective of this study is to compare 2 different approaches for hip replacement in patients having undergone bilateral Total Hip Arthroplasty (THA). The study will evaluate the effect of the anterior approach on long term outcomes, functional muscle testing and MRI evaluations.

  • Retrospective Chart/Radiographic Review of UKA
    The primary objective of this study is to evaluate several diagnoses, treatments, and outcomes related to partial osteoarthritis (OA) of the knee mostly on the inside of the knee, also known as unicompartmental OA or UKA.

  • Comparison of Robotically versus Manually Implanted Knee Replacement
    The primary objective of this study is to compare the clinical and radiographic outcomes of Unicondylar Knee Arthroplasty (UKA) also known as partial knee replacement in three patient groups, one undergoing implantation of an UKA under robotic guidance, one undergoing computer navigated Total Knee Arthrop (TKA), and one with traditional manual instrumentation. This study is also dubbed as the Functional Outcomes Study (FOS-Mako). Actively enrolling in this study.

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